(M35.6) Relapsing panniculitis [weber-christian]

Weber-christian disease, also known as relapsing panniculitis, is a rare disorder characterized by recurrent episodes of inflammation of the subcutaneous fat, which can lead to scarring and fibrosis. it is believed to be an autoimmune disorder in which the body's own immune system mistakenly attacks its own fat cells. symptoms can include fever, fatigue, joint pain, and skin lesions. treatment typically involves the use of corticosteroids, immunosuppressants, and antibiotics.

Relapsing panniculitis (weber-christian) is an inflammatory disorder of the subcutaneous fat. it is thought to be caused by an autoimmune process, in which the body's immune system mistakenly attacks the fat cells, leading to inflammation and subsequent fat necrosis. this process is characterized by recurrent episodes of inflammation followed by periods of remission. the exact cause of the autoimmune process is unknown, but is thought to be a combination of genetic and environmental factors.

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• Physical examination
• Blood tests to check for inflammation markers
• Imaging tests such as X-rays or CT scans
• Biopsy of the affected area
• Skin biopsy to check for changes in the fat cells
• Ultrasound scan to check for changes in the fat cells

Additional measures:

• Treatment with corticosteroids
• Immunosuppressive drugs
• Surgery to remove the affected tissue

Main goal: To reduce inflammation and decrease the number of relapses

• Prescribe corticosteroids to reduce inflammation
• Prescribe antibiotics to treat any secondary infections
• Encourage rest and relaxation
• Prescribe nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce inflammation and pain
• Prescribe antimalarial drugs to reduce inflammation
• Prescribe immunosuppressants to reduce the body's immune response
• Encourage regular exercise to improve overall health
• Prescribe colchicine to reduce inflammation
• Prescribe retinoids to reduce inflammation and help skin heal
• Prescribe vitamin A supplements to help skin heal
• Prescribe biologic medications to reduce inflammation and improve skin healing

Relapsing panniculitis [weber-christian] can be prevented by avoiding exposure to cold temperatures, avoiding stress, eating a healthy diet, and exercising regularly. additionally, patients should take steps to avoid infections, such as washing their hands regularly and avoiding contact with people who are ill.